Call 1-80 for expert advice from a regional poison control center. Certain manufacturers recommend use of filters during preparation and administration refer to specific product labeling to confirm need for filter. Visually inspect parenteral products for particulate matter and discoloration prior to administration whenever solution and container permit.

When used for cyanide toxicity, blood pressure must be monitored during treatment.įor storage information, see the specific product information within the How Supplied section. When used for ototoxicity prophylaxis, it must be separated from cisplatin administration by 6 to 10 hours due to decreased cytotoxicity of cisplatin to tumor cells. It is indicated as an antidote for cyanide toxicity and for the prevention of cisplatin-related ototoxicity in pediatric patients older than 1 month of age it may not reduce the risk of ototoxicity with cisplatin infusions longer than 6 hours, as irreversible ototoxicity may have already occurred. Sodium thiosulfate is a relatively nontoxic substance.

Sodium thiosulfate as poison antidote